racoon eyes neuroblastoma
View via Publisher. The clinical presentation will depend upon the location of metastases usually presenting with mass effect. Pdkxhaba2q1kcm Raccoon eyes occurs due to increased vascular fragility propagated by accumulation of amyloid fibrils34. . Orbital metastases can be seen in up to 20 of children with advanced stage of NB. It is worth noting however that in children the spread of systemic neuroblastoma is the most common cause of orbital metastases 4. 2 Neurologists should be aware of this sign and its differential. N Engl J Med. Save to Library Save. The majority of them demonstrate. Symptoms Symptoms of raccoon eyes include bruises primarily visible around the eyes. Kidneys are the most frequently involved organ and are seen in 7080 of the patients followed by the heart 50601 Macroglossia a pathognomonic sign of this. Metastatic neuroblastoma with opsoclonus raccoon eye presentation is an extremely